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EMD Biosciences Doxorubicin, Hydrochloride, Calbiochem, 10 mg, Model 324380-10MG, Each

Part Number VWR-80058-048
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EMD Biosciences Doxorubicin, Hydrochloride, Calbiochem, 10 mg, Model 324380-10MG, Each Synonyms 14-Hydroxydaunomycin, HCl

Product Form Red solid.
An antitumor antibiotic and a highly effective myotoxin that inhibits topoisomerase II (IC50=0.1uM). Binds to nucleic acids, presumably by specific intercalation into the DNA double helix, inhibiting nucleic acid synthesis. Induces apoptosis in rhabdomyosarcoma cell lines.
Purity Purity: >=95% by HPLC.
Solubility Soluble in water.

Formula C27H29NO11"¢HCl

Formula Weight 580.0
CAS Number 25316-40-9
Merck Index 12, 3495

Storage and Handling Store at 20 degrees C (68 degrees F). Protect from light.

Warning Harmful. LD50 of <=2000mg/kg. May be carcinogenic/teratogenic.

Literature References A'Hern, R. P., and Gore, M. E. 1995. J. Clin. Oncol. 13, 726; Nooter, K., et al. 1995. Br. J. Cancer 71, 556; Noviello, E., et al. 1994. Mutat. Res. 311, 21.

This is only for EMD Biosciences, Model 324380-10MG. It may differ from the image shown in color, features, may be an accessory, etc. Please refer to the model number or contact us if you have any questions.

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Description
Synonyms 14-Hydroxydaunomycin, HCl

Product Form Red solid.
An antitumor antibiotic and a highly effective myotoxin that inhibits topoisomerase II (IC50=0.1uM). Binds to nucleic acids, presumably by specific intercalation into the DNA double helix, inhibiting nucleic acid synthesis. Induces apoptosis in rhabdomyosarcoma cell lines.
Purity Purity: >=95% by HPLC.
Solubility Soluble in water.

Formula C27H29NO11"¢HCl

Formula Weight 580.0
CAS Number 25316-40-9
Merck Index 12, 3495

Storage and Handling Store at 20 degrees C (68 degrees F). Protect from light.

Warning Harmful. LD50 of <=2000mg/kg. May be carcinogenic/teratogenic.

Literature References A'Hern, R. P., and Gore, M. E. 1995. J. Clin. Oncol. 13, 726; Nooter, K., et al. 1995. Br. J. Cancer 71, 556; Noviello, E., et al. 1994. Mutat. Res. 311, 21.

This is only for EMD Biosciences, Model 324380-10MG. It may differ from the image shown in color, features, may be an accessory, etc. Please refer to the model number or contact us if you have any questions.

Feature: Berktree, LLC does not have a valid license to distribute prescription items.
Feature: This item is not for sale. It is displayed for information purposes only.
Feature: EMD Biosciences Doxorubicin, Hydrochloride, Calbiochem, 10 mg, Model 324380-10MG, Each
Feature: Size: 10 mg
Feature 5 This item is sold by the Each (10 MG)
Feature 6
Categorization: Media > Antibiotics and Antimycotics > Doxorubicin, Hydrochloride, Calbiochem
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